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TMEM87a/Elkin1, a component of a novel mechanoelectrical transduction pathway, modulates melanoma adhesion and migration

Mechanoelectrical transduction is a cellular signalling pathway where physical stimuli are converted into electro-chemical signals by mechanically activated ion channels. We describe here the presence of mechanically activated currents in melanoma cells that are dependent on TMEM87a, which we have r...

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Detalles Bibliográficos
Autores principales: Patkunarajah, Amrutha, Stear, Jeffrey H, Moroni, Mirko, Schroeter, Lioba, Blaszkiewicz, Jedrzej, Tearle, Jacqueline LE, Cox, Charles D, Fürst, Carina, Sánchez-Carranza, Oscar, Ocaña Fernández, María del Ángel, Fleischer, Raluca, Eravci, Murat, Weise, Christoph, Martinac, Boris, Biro, Maté, Lewin, Gary R, Poole, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173973/
https://www.ncbi.nlm.nih.gov/pubmed/32228863
http://dx.doi.org/10.7554/eLife.53308