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Adjuvantic cytokine IL-33 improves the protective immunity of cocktailed DNA vaccine of ROP5 and ROP18 against toxoplasma gondii infection in mice

Toxoplasma gondii is a threat for immunocompromized individuals, and no treatment is available for enhancing immunity against infection. Molecular adjuvants may improve the efficacy of DNA vaccine-induced T cell immunity. Here, we report that cocktailed DNA immunization with ROP5 and ROP18 boosted i...

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Detalles Bibliográficos
Autores principales: Zhu, Yu-Chao, He, Yong, Liu, Jian-Fa, Chen, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174000/
https://www.ncbi.nlm.nih.gov/pubmed/32315596
http://dx.doi.org/10.1051/parasite/2020021