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Characterization of human cancer xenografts in humanized mice

BACKGROUND: Preclinical evaluation of drugs targeting the human immune system has posed challenges for oncology researchers. Since the commercial introduction of humanized mice, antitumor efficacy and pharmacodynamic studies can now be performed with human cancer cells within mice bearing components...

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Detalles Bibliográficos
Autores principales: Rios-Doria, Jonathan, Stevens, Christina, Maddage, Christopher, Lasky, Kerri, Koblish, Holly K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174072/
https://www.ncbi.nlm.nih.gov/pubmed/32217760
http://dx.doi.org/10.1136/jitc-2019-000416