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Characterization of human cancer xenografts in humanized mice
BACKGROUND: Preclinical evaluation of drugs targeting the human immune system has posed challenges for oncology researchers. Since the commercial introduction of humanized mice, antitumor efficacy and pharmacodynamic studies can now be performed with human cancer cells within mice bearing components...
Autores principales: | Rios-Doria, Jonathan, Stevens, Christina, Maddage, Christopher, Lasky, Kerri, Koblish, Holly K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174072/ https://www.ncbi.nlm.nih.gov/pubmed/32217760 http://dx.doi.org/10.1136/jitc-2019-000416 |
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