The insufficiency of circulating miRNA and DNA as diagnostic tools or as biomarkers of treatment efficacy for Onchocerca volvulus

Skin snip evaluation for onchocerciasis has insufficient sensitivity when skin microfilarial (mf) densities are low, such as following ivermectin treatment. Mf density is suitable for assessing microfilaricidal efficacy but only serves as an indirect indicator of macrofilaricidal activity. We assess...

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Detalles Bibliográficos
Autores principales: Macfarlane, Cara L., Quek, Shannon, Pionnier, Nicolas, Turner, Joseph D., Wanji, Samuel, Wagstaff, Simon C., Taylor, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174290/
https://www.ncbi.nlm.nih.gov/pubmed/32317658
http://dx.doi.org/10.1038/s41598-020-63249-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174290/
https://www.ncbi.nlm.nih.gov/pubmed/32317658
http://dx.doi.org/10.1038/s41598-020-63249-4

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