Neuroprotective effect of alogliptin on oxaliplatin-induced peripheral neuropathy in vivo and in vitro

Oxaliplatin is a platinum-based antineoplastic drug commonly used for treating colorectal, gastric, and pancreatic cancer. However, it frequently causes peripheral neuropathy as dose-limiting toxicity and is lacking a strategy for prevention. Alogliptin, a dipeptidyl peptidase 4 (DPP-4) inhibitor, i...

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Detalles Bibliográficos
Autores principales: Shigematsu, Nao, Kawashiri, Takehiro, Kobayashi, Daisuke, Shimizu, Shiori, Mine, Keisuke, Hiromoto, Shiori, Uchida, Mayako, Egashira, Nobuaki, Shimazoe, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174301/
https://www.ncbi.nlm.nih.gov/pubmed/32317735
http://dx.doi.org/10.1038/s41598-020-62738-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174301/
https://www.ncbi.nlm.nih.gov/pubmed/32317735
http://dx.doi.org/10.1038/s41598-020-62738-w

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