Cargando…

Mismatched and wobble base pairs govern primary microRNA processing by human Microprocessor

MicroRNAs (miRNAs) are small RNAs that regulate gene expression. miRNAs are produced from primary miRNAs (pri-miRNAs), which are cleaved by Microprocessor. Microprocessor, therefore, plays a crucial role in determining the efficiency and precision of miRNA production, and thus the function of the fi...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Shaohua, Nguyen, Trung Duc, Nguyen, Thuy Linh, Nguyen, Tuan Anh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174388/
https://www.ncbi.nlm.nih.gov/pubmed/32317642
http://dx.doi.org/10.1038/s41467-020-15674-2