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Mismatched and wobble base pairs govern primary microRNA processing by human Microprocessor
MicroRNAs (miRNAs) are small RNAs that regulate gene expression. miRNAs are produced from primary miRNAs (pri-miRNAs), which are cleaved by Microprocessor. Microprocessor, therefore, plays a crucial role in determining the efficiency and precision of miRNA production, and thus the function of the fi...
Autores principales: | Li, Shaohua, Nguyen, Trung Duc, Nguyen, Thuy Linh, Nguyen, Tuan Anh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174388/ https://www.ncbi.nlm.nih.gov/pubmed/32317642 http://dx.doi.org/10.1038/s41467-020-15674-2 |
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