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NUSAP1 potentiates chemoresistance in glioblastoma through its SAP domain to stabilize ATR

NUSAP1, which is a microtubule-associated protein involved in mitosis, plays essential roles in diverse biological processes, especially in cancer biology. In this study, NUSAP1 was found to be overexpressed in GBM tissues in a grade-dependent manner compared with normal brain tissues. NUSAP1 was al...

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Detalles Bibliográficos
Autores principales: Zhao, Yuzu, He, Jiang, Li, Yongsen, Lv, Shengqing, Cui, Hongjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174393/
https://www.ncbi.nlm.nih.gov/pubmed/32317623
http://dx.doi.org/10.1038/s41392-020-0137-7