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MG132 exerts anti-viral activity against HSV-1 by overcoming virus-mediated suppression of the ERK signaling pathway

Herpes simplex virus 1 (HSV-1) causes a number of clinical manifestations including cold sores, keratitis, meningitis and encephalitis. Although current drugs are available to treat HSV-1 infection, they can cause side effects such as nephrotoxicity. Moreover, owing to the emergence of drug-resistan...

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Detalles Bibliográficos
Autores principales: Ishimaru, Hanako, Hosokawa, Kohei, Sugimoto, Atsuko, Tanaka, Riho, Watanabe, Tadashi, Fujimuro, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174428/
https://www.ncbi.nlm.nih.gov/pubmed/32317666
http://dx.doi.org/10.1038/s41598-020-63438-1