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Hypertension and Pathogenic hAPP Independently Induce White Matter Astrocytosis and Cognitive Impairment in the Rat

Hypertension is recognized as a risk factor for Alzheimer disease, but the causal link remains undetermined. Although astrocytes and microglia play an important role in maintaining the neurovascular unit, astrocytes and microglia have been understudied in comorbid models of hypertension and Alzheime...

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Detalles Bibliográficos
Autores principales: Levit, Alexander, Cheng, Sonny, Hough, Olivia, Liu, Qingfan, Agca, Yuksel, Agca, Cansu, Hachinski, Vladimir, Whitehead, Shawn N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174625/
https://www.ncbi.nlm.nih.gov/pubmed/32351378
http://dx.doi.org/10.3389/fnagi.2020.00082