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Tolerance to FVIII: Role of the Immune Metabolic Enzymes Indoleamine 2,3 Dyoxigenase-1 and Heme Oxygenase-1

The occurrence of neutralizing anti-FVIII antibodies is a major complication in the treatment of patients affected by hemophilia A. The immune response to FVIII is a complex, multi-factorial process that has been extensively studied for the past two decades. The reasons why only a proportion of hemo...

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Detalles Bibliográficos
Autores principales: Matino, Davide, Afraz, Sajjad, Zhao, George, Tieu, Paul, Gargaro, Marco, Fallarino, Francesca, Iorio, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174632/
https://www.ncbi.nlm.nih.gov/pubmed/32351505
http://dx.doi.org/10.3389/fimmu.2020.00620