Dynamic Modeling of CHO Cell Metabolism Using the Hybrid Cybernetic Approach With a Novel Elementary Mode Analysis Strategy

Chinese hamster ovary (CHO) cell culture has a major importance on the production of biopharmaceuticals, including recombinant therapeutic proteins such as monoclonal antibodies (MAb). Mathematical modeling of biological systems can successfully assess metabolism complexity while providing logical a...

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Detalles Bibliográficos
Autores principales: Martínez, Juan A., Bulté, Dubhe B., Contreras, Martha A., Palomares, Laura A., Ramírez, Octavio T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174696/
https://www.ncbi.nlm.nih.gov/pubmed/32351947
http://dx.doi.org/10.3389/fbioe.2020.00279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174696/
https://www.ncbi.nlm.nih.gov/pubmed/32351947
http://dx.doi.org/10.3389/fbioe.2020.00279

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