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Pregabalin as a Pain Therapeutic: Beyond Calcium Channels

Initially developed to generate new treatments for epilepsy, gabapentin, and pregabalin (“gabapentinoids”) were engineered to mimic the action of GABA and to modulate GABA metabolism. Rather than their intended pharmacological action on GABA neurotransmission, instead, they exhibit a high affinity f...

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Detalles Bibliográficos
Autores principales: Alles, Sascha R. A., Cain, Stuart M., Snutch, Terrance P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174704/
https://www.ncbi.nlm.nih.gov/pubmed/32351366
http://dx.doi.org/10.3389/fncel.2020.00083