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Pregabalin as a Pain Therapeutic: Beyond Calcium Channels
Initially developed to generate new treatments for epilepsy, gabapentin, and pregabalin (“gabapentinoids”) were engineered to mimic the action of GABA and to modulate GABA metabolism. Rather than their intended pharmacological action on GABA neurotransmission, instead, they exhibit a high affinity f...
Autores principales: | Alles, Sascha R. A., Cain, Stuart M., Snutch, Terrance P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174704/ https://www.ncbi.nlm.nih.gov/pubmed/32351366 http://dx.doi.org/10.3389/fncel.2020.00083 |
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