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A New Rat Model of Chronic Cerebral Hypoperfusion Resulting in Early-Stage Vascular Cognitive Impairment

OBJECTIVE: Currently, most models of vascular cognitive impairment are established by occluding the carotid arteries uni- or bilaterally to reduce the cerebral blood flow mimicking chronic cerebral hypoxia. Due to the sudden blood flow interruption, a gradual narrowing of the carotid artery cannot b...

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Detalles Bibliográficos
Autores principales: Wang, Jinxin, Yang, Chenyi, Wang, Haiyun, Li, Dongxue, Li, Tang, Sun, Yi, Zhao, Mingshu, Ma, Ji, Hua, Wei, Yang, Zhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174718/
https://www.ncbi.nlm.nih.gov/pubmed/32351379
http://dx.doi.org/10.3389/fnagi.2020.00086