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Human Regulatory T Cells From Umbilical Cord Blood Display Increased Repertoire Diversity and Lineage Stability Relative to Adult Peripheral Blood

The human T lymphocyte compartment is highly dynamic over the course of a lifetime. Of the many changes, perhaps most notable is the transition from a predominantly naïve T cell state at birth to the acquisition of antigen-experienced memory and effector subsets following environmental exposures. Th...

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Detalles Bibliográficos
Autores principales: Motwani, Keshav, Peters, Leeana D., Vliegen, Willem H., El-sayed, Ahmed Gomaa, Seay, Howard R., Lopez, M. Cecilia, Baker, Henry V., Posgai, Amanda L., Brusko, Maigan A., Perry, Daniel J., Bacher, Rhonda, Larkin, Joseph, Haller, Michael J., Brusko, Todd M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174770/
https://www.ncbi.nlm.nih.gov/pubmed/32351504
http://dx.doi.org/10.3389/fimmu.2020.00611