DPP4 Inhibition, NPY(1-36), PYY(1-36), SDF-1α, and a Hypertensive Genetic Background Conspire to Augment Cell Proliferation and Collagen Production: Effects That Are Abolished by Low Concentrations of 2-Methoxyestradiol

By reducing their metabolism, dipeptidyl peptidase 4 inhibition (DPP4I) enhances the effects of numerous peptides including neuropeptide Y(1–36) (NPY(1–36)), peptide YY(1–36) (PYY(1–36)), and SDF-1α. Studies show that separately NPY(1–36), PYY(1–36) and SDF-1α stimulate proliferation of, and collage...

Descripción completa

Detalles Bibliográficos
Autores principales: Jackson, Edwin K., Gillespie, Delbert G., Tofovic, Stevan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2020
Materias:
Cardiovascular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174788/
https://www.ncbi.nlm.nih.gov/pubmed/32015161
http://dx.doi.org/10.1124/jpet.119.263467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174788/
https://www.ncbi.nlm.nih.gov/pubmed/32015161
http://dx.doi.org/10.1124/jpet.119.263467

Ejemplares similares