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DPP4 Inhibition, NPY(1-36), PYY(1-36), SDF-1α, and a Hypertensive Genetic Background Conspire to Augment Cell Proliferation and Collagen Production: Effects That Are Abolished by Low Concentrations of 2-Methoxyestradiol
By reducing their metabolism, dipeptidyl peptidase 4 inhibition (DPP4I) enhances the effects of numerous peptides including neuropeptide Y(1–36) (NPY(1–36)), peptide YY(1–36) (PYY(1–36)), and SDF-1α. Studies show that separately NPY(1–36), PYY(1–36) and SDF-1α stimulate proliferation of, and collage...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174788/ https://www.ncbi.nlm.nih.gov/pubmed/32015161 http://dx.doi.org/10.1124/jpet.119.263467 |