Analysis of C-Kit Exon 9, Exon 11 and BRAFV600E Mutations Using Sangers Sequencing in Gastrointestinal Stromal Tumours

Background Gastrointestinal stromal tumors (GIST) are the most common mesenchymal neoplasms in the gastrointestinal (GI) tract. The mutation of C-KIT is considered to be the crucial step in the tumorigenesis. Targeted therapies are being developed focusing these mutations. Various exon mutations of...

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Detalles Bibliográficos
Autores principales: Madhala, Divya, Sundaram, Sandhya, Chinambedudandapani, MohanaPriya, Balasubramanian, Archana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174865/
https://www.ncbi.nlm.nih.gov/pubmed/32328381
http://dx.doi.org/10.7759/cureus.7369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174865/
https://www.ncbi.nlm.nih.gov/pubmed/32328381
http://dx.doi.org/10.7759/cureus.7369

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