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Treatment with anti‐neonatal Fc receptor (FcRn) antibody ameliorates experimental epidermolysis bullosa acquisita in mice

BACKGROUND AND PURPOSE: Pemphigus and pemphigoid diseases are characterized and caused predominantly by IgG autoantibodies targeting structural proteins of the skin. Their current treatment relies on general and prolonged immunosuppression that causes severe adverse events, including death. Hence, n...

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Detalles Bibliográficos
Autores principales: Kasprick, Anika, Hofrichter, Maxi, Smith, Bryan, Ward, Penelope, Bieber, Katja, Shock, Anthony, Ludwig, Ralf J., Schmidt, Enno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174883/
https://www.ncbi.nlm.nih.gov/pubmed/31975370
http://dx.doi.org/10.1111/bph.14986