CYP2A13 Acts as the Main Metabolic CYP450s Enzyme for Activating Leonurine in Human Bronchial Epithelial Cells

BACKGROUND: Leonurine is an active component of the traditional Chinese medicine Leonurus japonicus. This study aimed to investigate the effects of overexpressed CYP450s on the metabolic activity of leonurine. MATERIAL/METHODS: BEAS-2B cells stably expressing CYP1A1, 1A2, 2A13, 2B6, and 3A4 were con...

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Detalles Bibliográficos
Autores principales: Xu, Ting, Li, Xuxu, Leng, Tian, Zhuang, Tianchi, Sun, Yan, Tang, Yajun, Wang, Li, Yang, Muyi, Ji, Minghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174896/
https://www.ncbi.nlm.nih.gov/pubmed/32284524
http://dx.doi.org/10.12659/MSM.922149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7174896/
https://www.ncbi.nlm.nih.gov/pubmed/32284524
http://dx.doi.org/10.12659/MSM.922149

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