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Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion
2p16.3 deletions, involving heterozygous NEUREXIN1 (NRXN1) deletion, dramatically increase the risk of developing neurodevelopmental disorders, including autism and schizophrenia. We have little understanding of how NRXN1 heterozygosity increases the risk of developing these disorders, particularly...
Autores principales: | B Hughes, Rebecca, Whittingham-Dowd, Jayde, Simmons, Rachel E, Clapcote, Steven J, Broughton, Susan J, Dawson, Neil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175007/ https://www.ncbi.nlm.nih.gov/pubmed/31812984 http://dx.doi.org/10.1093/cercor/bhz244 |
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