Ehrlichia chaffeensis Uses an Invasin To Suppress Reactive Oxygen Species Generation by Macrophages via CD147-Dependent Inhibition of Vav1 To Block Rac1 Activation

The obligatory intracellular pathogen Ehrlichia chaffeensis lacks most factors that could respond to oxidative stress (a host cell defense mechanism). We previously found that the C terminus of Ehrlichia surface invasin, entry-triggering protein of Ehrlichia (EtpE; EtpE-C) directly binds mammalian D...

Descripción completa

Detalles Bibliográficos
Autores principales: Teymournejad, Omid, Rikihisa, Yasuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175088/
https://www.ncbi.nlm.nih.gov/pubmed/32317318
http://dx.doi.org/10.1128/mBio.00267-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175088/
https://www.ncbi.nlm.nih.gov/pubmed/32317318
http://dx.doi.org/10.1128/mBio.00267-20

Ejemplares similares