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Interplay between Endoplasmic Reticulum (ER) Stress and Autophagy Induces Mutant p53H273 Degradation

The unfolded protein response (UPR) is an adaptive response to intrinsic and external stressors, and it is mainly activated by the accumulation of misfolded proteins at the endoplasmic reticulum (ER) lumen producing ER stress. The UPR signaling network is interconnected with autophagy, the proteolyt...

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Detalles Bibliográficos
Autores principales: Garufi, Alessia, Federici, Giulia, Gilardini Montani, Maria Saveria, Crispini, Alessandra, Cirone, Mara, D’Orazi, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175121/
https://www.ncbi.nlm.nih.gov/pubmed/32138264
http://dx.doi.org/10.3390/biom10030392