Synthesis, In Vitro Evaluation and Molecular Docking of the 5-Acetyl-2-aryl-6-hydroxybenzo[b]furans against Multiple Targets Linked to Type 2 Diabetes

The 5-acetyl-2-aryl-6-hydroxybenzo[b]furans 2a–h have been evaluated through in vitro enzymatic assay against targets which are linked to type 2 diabetes (T2D), namely, α-glucosidase, protein tyrosine phosphatase 1B (PTP1B) and β-secretase. These compounds have also been evaluated for antioxidant ac...

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Detalles Bibliográficos
Autores principales: Mphahlele, Malose J., Choong, Yee Siew, Maluleka, Marole M., Gildenhuys, Samantha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175131/
https://www.ncbi.nlm.nih.gov/pubmed/32156083
http://dx.doi.org/10.3390/biom10030418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175131/
https://www.ncbi.nlm.nih.gov/pubmed/32156083
http://dx.doi.org/10.3390/biom10030418

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