NAD- and NADPH-Contributing Enzymes as Therapeutic Targets in Cancer: An Overview

Actively proliferating cancer cells require sufficient amount of NADH and NADPH for biogenesis and to protect cells from the detrimental effect of reactive oxygen species. As both normal and cancer cells share the same NAD biosynthetic and metabolic pathways, selectively lowering levels of NAD(H) an...

Descripción completa

Detalles Bibliográficos
Autores principales: Pramono, Alvinsyah Adhityo, Rather, Gulam M., Herman, Herry, Lestari, Keri, Bertino, Joseph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175141/
https://www.ncbi.nlm.nih.gov/pubmed/32111066
http://dx.doi.org/10.3390/biom10030358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175141/
https://www.ncbi.nlm.nih.gov/pubmed/32111066
http://dx.doi.org/10.3390/biom10030358

Ejemplares similares