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Testing the Pharmacokinetic Interactions of 24 Colonic Flavonoid Metabolites with Human Serum Albumin and Cytochrome P450 Enzymes

Flavonoids are abundant polyphenols in nature. They are extensively biotransformed in enterocytes and hepatocytes, where conjugated (methyl, sulfate, and glucuronide) metabolites are formed. However, bacterial microflora in the human intestines also metabolize flavonoids, resulting in the production...

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Detalles Bibliográficos
Autores principales: Mohos, Violetta, Fliszár-Nyúl, Eszter, Lemli, Beáta, Zsidó, Balázs Zoltán, Hetényi, Csaba, Mladěnka, Přemysl, Horký, Pavel, Pour, Milan, Poór, Miklós
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175153/
https://www.ncbi.nlm.nih.gov/pubmed/32155912
http://dx.doi.org/10.3390/biom10030409