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Testing the Pharmacokinetic Interactions of 24 Colonic Flavonoid Metabolites with Human Serum Albumin and Cytochrome P450 Enzymes
Flavonoids are abundant polyphenols in nature. They are extensively biotransformed in enterocytes and hepatocytes, where conjugated (methyl, sulfate, and glucuronide) metabolites are formed. However, bacterial microflora in the human intestines also metabolize flavonoids, resulting in the production...
Autores principales: | Mohos, Violetta, Fliszár-Nyúl, Eszter, Lemli, Beáta, Zsidó, Balázs Zoltán, Hetényi, Csaba, Mladěnka, Přemysl, Horký, Pavel, Pour, Milan, Poór, Miklós |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175153/ https://www.ncbi.nlm.nih.gov/pubmed/32155912 http://dx.doi.org/10.3390/biom10030409 |
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