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A Bioorthogonally Applicable, Fluorogenic, Large Stokes-Shift Probe for Intracellular Super-Resolution Imaging of Proteins

Herein, we present the synthesis and application of a fluorogenic, large Stokes-shift (>100 nm), bioorthogonally conjugatable, membrane-permeable tetrazine probe, which can be excited at common laser line 488 nm and detected at around 600 nm. The applied design enabled improved fluorogenicity in...

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Detalles Bibliográficos
Autores principales: Németh, Evelin, Knorr, Gergely, Németh, Krisztina, Kele, Péter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175155/
https://www.ncbi.nlm.nih.gov/pubmed/32143419
http://dx.doi.org/10.3390/biom10030397