Mutant p53-Associated Molecular Mechanisms of ROS Regulation in Cancer Cells

The TP53 tumor suppressor gene is the most frequently altered gene in tumors and an increasing number of studies highlight that mutant p53 proteins can acquire oncogenic properties, referred to as gain-of-function (GOF). Reactive oxygen species (ROS) play critical roles as intracellular messengers,...

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Detalles Bibliográficos
Autores principales: Cordani, Marco, Butera, Giovanna, Pacchiana, Raffaella, Masetto, Francesca, Mullappilly, Nidula, Riganti, Chiara, Donadelli, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175157/
https://www.ncbi.nlm.nih.gov/pubmed/32111081
http://dx.doi.org/10.3390/biom10030361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175157/
https://www.ncbi.nlm.nih.gov/pubmed/32111081
http://dx.doi.org/10.3390/biom10030361

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