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PIRT the TRP Channel Regulating Protein Binds Calmodulin and Cholesterol-Like Ligands

Transient receptor potential (TRP) ion channels are polymodal receptors that have been implicated in a variety of pathophysiologies, including pain, obesity, and cancer. The capsaicin and heat sensor TRPV1, and the menthol and cold sensor TRPM8, have been shown to be modulated by the membrane protei...

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Detalles Bibliográficos
Autores principales: Sisco, Nicholas J., Luu, Dustin D., Kim, Minjoo, Van Horn, Wade D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175203/
https://www.ncbi.nlm.nih.gov/pubmed/32245175
http://dx.doi.org/10.3390/biom10030478