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Trends in the Recent Patent Literature on Cholinesterase Reactivators (2016–2019)

Acetylcholinesterase (AChE) is the key enzyme responsible for deactivating the ACh neurotransmitter. Irreversible or prolonged inhibition of AChE, therefore, elevates synaptic ACh leading to serious central and peripheral adverse effects which fall under the cholinergic syndrome spectra. To combat t...

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Detalles Bibliográficos
Autores principales: de Castro, Alexandre A., Assis, Letícia C., Soares, Flávia V., Kuca, Kamil, Polisel, Daniel A., da Cunha, Elaine F. F., Ramalho, Teodorico C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175240/
https://www.ncbi.nlm.nih.gov/pubmed/32178264
http://dx.doi.org/10.3390/biom10030436