2-Oxoester Phospholipase A(2) Inhibitors with Enhanced Metabolic Stability

2-Oxoesters constitute an important class of potent and selective inhibitors of human cytosolic phospholipase A(2) (GIVA cPLA(2)) combining an aromatic scaffold or a long aliphatic chain with a short aliphatic chain containing a free carboxylic acid. Although highly potent 2-oxoester inhibitors of G...

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Detalles Bibliográficos
Autores principales: Koutoulogenis, Giorgos S., Kokotou, Maroula G., Hayashi, Daiki, Mouchlis, Varnavas D., Dennis, Edward A., Kokotos, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175278/
https://www.ncbi.nlm.nih.gov/pubmed/32213911
http://dx.doi.org/10.3390/biom10030491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175278/
https://www.ncbi.nlm.nih.gov/pubmed/32213911
http://dx.doi.org/10.3390/biom10030491

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