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Exposure to CuO Nanoparticles Mediates NFκB Activation and Enhances Amyloid Precursor Protein Expression

Amyloid precursor protein (APP) is directly related to Aβ amyloidosis—a hallmark of Alzheimer’s disease (AD). However, the impact of environmental factors upon APP biology and Aβ amyloid pathology have not been well studied. The increased use of nanoparticles (NPs) or engineered nanomaterials (ENMs)...

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Detalles Bibliográficos
Autores principales: Mou, Xiaoyang, Pilozzi, Alexander, Tailor, Breeya, Yi, Jing, Cahill, Catherine, Rogers, Jack, Huang, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175332/
https://www.ncbi.nlm.nih.gov/pubmed/32120908
http://dx.doi.org/10.3390/biomedicines8030045