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Why Does Knocking Out NACHO, But Not RIC3, Completely Block Expression of α7 Nicotinic Receptors in Mouse Brain?

Alpha7 nicotinic acetylcholine receptors (α7nAChRs) are interesting not only because of their physiological effects, but because this receptor requires chaperones to traffic to cell surfaces (measured by alpha-bungarotoxin [αBGT] binding). While knockout (KO) animals and antibodies that react across...

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Detalles Bibliográficos
Autores principales: Deshpande, Anish, Vinayakamoorthy, Remitha M., Garg, Brijesh K., Thummapudi, Jaya Prakash, Oza, Gauri, Adhikari, Ketaki, Agarwal, Aayush, Dalvi, Parnika, Iyer, Swetha, Thulasi Raman, Sarulatha, Ramesh, Vijay, Rameshbabu, Akshitha, Rezvaya, Alexandra, Sukumaran, Sneha, Swaminathan, Sweta, Tilak, Bhargav, Wang, Zhiyuan, Tran, Phu V., Loring, Ralph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175337/
https://www.ncbi.nlm.nih.gov/pubmed/32204458
http://dx.doi.org/10.3390/biom10030470