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Genome-wide DNA methylation profiles of low- and high-grade adenoma reveals potential biomarkers for early detection of colorectal carcinoma

BACKGROUND: Abnormal DNA methylation is a hallmark of human cancers and may be a promising biomarker for early diagnosis of human cancers. However, the majority of DNA methylation biomarkers that have been identified are based on the hypothesis that early differential methylation regions (DMRs) are...

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Detalles Bibliográficos
Autores principales: Fan, Jian, Li, Jun, Guo, Shicheng, Tao, Chengcheng, Zhang, Haikun, Wang, Wenjing, Zhang, Ying, Zhang, Dake, Ding, Shigang, Zeng, Changqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175491/
https://www.ncbi.nlm.nih.gov/pubmed/32317010
http://dx.doi.org/10.1186/s13148-020-00851-3