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Participation of the ATR/CHK1 pathway in replicative stress targeted therapy of high-grade ovarian cancer

Ovarian cancer is one of the most lethal gynecologic malignancies reported throughout the world. The initial, standard-of-care, adjuvant chemotherapy in epithelial ovarian cancer is usually a platinum drug, such as cisplatin or carboplatin, combined with a taxane. However, despite surgical removal o...

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Detalles Bibliográficos
Autores principales: Gralewska, Patrycja, Gajek, Arkadiusz, Marczak, Agnieszka, Rogalska, Aneta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175546/
https://www.ncbi.nlm.nih.gov/pubmed/32316968
http://dx.doi.org/10.1186/s13045-020-00874-6