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Participation of the ATR/CHK1 pathway in replicative stress targeted therapy of high-grade ovarian cancer
Ovarian cancer is one of the most lethal gynecologic malignancies reported throughout the world. The initial, standard-of-care, adjuvant chemotherapy in epithelial ovarian cancer is usually a platinum drug, such as cisplatin or carboplatin, combined with a taxane. However, despite surgical removal o...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175546/ https://www.ncbi.nlm.nih.gov/pubmed/32316968 http://dx.doi.org/10.1186/s13045-020-00874-6 |