GPR30 receptor promotes preoperative anxiety-induced postoperative hyperalgesia by up-regulating GABA(A)-α4β1δ subunits in periaqueductal gray in female rats

BACKGROUND: G-protein coupled estrogen receptor 30 (GPR30) was proved the specific estrogen receptor relating to mechanical hyperalgesia. Studies have shown that the GABA(A) receptor subunits α4, β1, and δ in the periaqueductal gray (PAG) neurons promote the descending facilitation system. This stud...

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Detalles Bibliográficos
Autores principales: Jiang, Ming, Sun, Yu’e, Lei, Yishan, Hu, Fan, Xia, Zhengrong, Liu, Yue, Ma, Zhengliang, Gu, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175561/
https://www.ncbi.nlm.nih.gov/pubmed/32321426
http://dx.doi.org/10.1186/s12871-020-01017-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175561/
https://www.ncbi.nlm.nih.gov/pubmed/32321426
http://dx.doi.org/10.1186/s12871-020-01017-7

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