Mouse connective tissue mast cell proteases tryptase and carboxypeptidase A3 play protective roles in itch induced by endothelin-1

BACKGROUND: Itch is an unpleasant sensation that can be debilitating, especially if it is chronic and of non-histaminergic origin, as treatment options are limited. Endothelin-1 (ET-1) is a potent endogenous vasoconstrictor that also has the ability to induce a burning, non-histaminergic pruritus wh...

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Detalles Bibliográficos
Autores principales: Magnúsdóttir, Elín I., Grujic, Mirjana, Bergman, Jessica, Pejler, Gunnar, Lagerström, Malin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175568/
https://www.ncbi.nlm.nih.gov/pubmed/32321525
http://dx.doi.org/10.1186/s12974-020-01795-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175568/
https://www.ncbi.nlm.nih.gov/pubmed/32321525
http://dx.doi.org/10.1186/s12974-020-01795-4

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