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Arginine is neuroprotective through suppressing HIF-1α/LDHA-mediated inflammatory response after cerebral ischemia/reperfusion injury

Neuroinflammation is a secondary response following ischemia stroke. Arginine is a non-essential amino acid that has been shown to inhibit acute inflammatory reaction. In this study we show that arginine treatment decreases neuronal death after rat cerebral ischemia/reperfusion (I/R) injury and impr...

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Detalles Bibliográficos
Autores principales: Chen, Song-Feng, Pan, Meng-Xian, Tang, Jun-Chun, Cheng, Jing, Zhao, Dan, Zhang, Ya, Liao, Hua-Bao, Liu, Rui, Zhuang, Yang, Zhang, Zhi-Feng, Chen, Juan, Lei, Rui-Xue, Li, Shi-Fang, Li, Huan-Ting, Wang, Ze-Fen, Wan, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175589/
https://www.ncbi.nlm.nih.gov/pubmed/32321555
http://dx.doi.org/10.1186/s13041-020-00601-9