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COVID-19: A New Virus, but a Familiar Receptor and Cytokine Release Syndrome

Zhou et al. (Nature) and Hoffmann et al. (Cell) identify ACE2 as a SARS-CoV-2 receptor, and the latter show its entry mechanism depends on cellular serine protease TMPRSS2. These results may explain proinflammatory cytokine release via the associated angiotestin II pathway and a possible therapeutic...

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Detalles Bibliográficos
Autores principales: Hirano, Toshio, Murakami, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175868/
https://www.ncbi.nlm.nih.gov/pubmed/32325025
http://dx.doi.org/10.1016/j.immuni.2020.04.003