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COVID-19: A New Virus, but a Familiar Receptor and Cytokine Release Syndrome
Zhou et al. (Nature) and Hoffmann et al. (Cell) identify ACE2 as a SARS-CoV-2 receptor, and the latter show its entry mechanism depends on cellular serine protease TMPRSS2. These results may explain proinflammatory cytokine release via the associated angiotestin II pathway and a possible therapeutic...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175868/ https://www.ncbi.nlm.nih.gov/pubmed/32325025 http://dx.doi.org/10.1016/j.immuni.2020.04.003 |