PRKAG2 Gene Expression Is Elevated and its Protein Levels Are Associated with Increased Amyloid-β Accumulation in the Alzheimer’s Disease Brain

Increased amyloid-β (Aβ) accumulation associated with abnormal autophagy-lysosomal activity and nutrient kinase dysregulation are common features in Alzheimer’s disease (AD) brain. Recent studies have identified PRKAG2 and TIPRL genes that control nutrient kinase regulated autophagy, and here we det...

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Detalles Bibliográficos
Autores principales: Bharadwaj, Prashant, Martins, Ralph N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175932/
https://www.ncbi.nlm.nih.gov/pubmed/32039845
http://dx.doi.org/10.3233/JAD-190948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175932/
https://www.ncbi.nlm.nih.gov/pubmed/32039845
http://dx.doi.org/10.3233/JAD-190948

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