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Endosome motility defects revealed at super-resolution in live cells using HIDE probes

We report new lipid-based, high-density, environmentally sensitive (HIDE) probes that accurately and selectively image endo-lysosomes and their dynamics at super-resolution for extended times. Treatment of live cells with the small molecules DiIC(16)TCO or DiIC(16’)TCO followed by in situ tetrazine...

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Detalles Bibliográficos
Autores principales: Gupta, Aarushi, Rivera-Molina, Felix, Xi, Zhiqun, Toomre, Derek, Schepartz, Alanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176048/
https://www.ncbi.nlm.nih.gov/pubmed/32094922
http://dx.doi.org/10.1038/s41589-020-0479-z