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NFE2L2 activator RS9 protects against corneal epithelial cell damage in dry eye models

Oxidative stress may cause ocular surface damage during the development of dry eye. Mammalian cells have defense systems against oxidative stress. A central regulator of the stress response is nuclear factor-erythroid 2-related factor 2 (NFE2L2). NFE2L2 is activated by the novel triterpenoid RS9 (a...

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Detalles Bibliográficos
Autores principales: Matsuda, Yuka, Machida, Mamiko, Nakagami, Yasuhiro, Nakajima, Takeshi, Azuma, Mitsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176120/
https://www.ncbi.nlm.nih.gov/pubmed/32320433
http://dx.doi.org/10.1371/journal.pone.0229421