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NFE2L2 activator RS9 protects against corneal epithelial cell damage in dry eye models
Oxidative stress may cause ocular surface damage during the development of dry eye. Mammalian cells have defense systems against oxidative stress. A central regulator of the stress response is nuclear factor-erythroid 2-related factor 2 (NFE2L2). NFE2L2 is activated by the novel triterpenoid RS9 (a...
Autores principales: | Matsuda, Yuka, Machida, Mamiko, Nakagami, Yasuhiro, Nakajima, Takeshi, Azuma, Mitsuyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176120/ https://www.ncbi.nlm.nih.gov/pubmed/32320433 http://dx.doi.org/10.1371/journal.pone.0229421 |
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