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Quaternary Structure of the SARS Coronavirus Main Protease

The maturation of the SARS coronavirus (CoV) involves the autocleavage of polyproteins 1a and 1ab by a main protease and papain-like protease. The functional unit of the main protease is a dimer in which each subunit has a Cys145–His41 catalytic dyad, with His41 acting as a general base. There is al...

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Detalles Bibliográficos
Autor principal: Chang, Gu-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176230/
http://dx.doi.org/10.1007/978-3-642-03683-5_8