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Increases in [IP(3)](i) aggravates diastolic [Ca(2+)] and contractile dysfunction in Chagas’ human cardiomyocytes

Chagas cardiomyopathy is the most severe manifestation of human Chagas disease and represents the major cause of morbidity and mortality in Latin America. We previously demonstrated diastolic Ca(2+) alterations in cardiomyocytes isolated from Chagas’ patients to different degrees of cardiac dysfunct...

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Detalles Bibliográficos
Autores principales: Mijares, Alfredo, Espinosa, Raúl, Adams, José, Lopez, José R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176279/
https://www.ncbi.nlm.nih.gov/pubmed/32275663
http://dx.doi.org/10.1371/journal.pntd.0008162