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Increases in [IP(3)](i) aggravates diastolic [Ca(2+)] and contractile dysfunction in Chagas’ human cardiomyocytes
Chagas cardiomyopathy is the most severe manifestation of human Chagas disease and represents the major cause of morbidity and mortality in Latin America. We previously demonstrated diastolic Ca(2+) alterations in cardiomyocytes isolated from Chagas’ patients to different degrees of cardiac dysfunct...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176279/ https://www.ncbi.nlm.nih.gov/pubmed/32275663 http://dx.doi.org/10.1371/journal.pntd.0008162 |