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A powerful and versatile colocalization test

Transcriptome-wide association studies (TWAS and PrediXcan) have been increasingly applied to detect associations between genetically predicted gene expressions and GWAS traits, which may suggest, however do not completely determine, causal genes for GWAS traits, due to the likely violation of their...

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Detalles Bibliográficos
Autores principales: Deng, Yangqing, Pan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176287/
https://www.ncbi.nlm.nih.gov/pubmed/32275709
http://dx.doi.org/10.1371/journal.pcbi.1007778